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quality Category:1977 films Category:Indian films Category:1970s Hindi-language filmsThe quinolone antibacterial agent nalidixic acid has been used to treat urinary tract infections. The antibiotic can cause teratogenicity in humans, and may induce chondrodysplasia in rats, pigs and calves. It is also an antitumorigenic agent. The quinolones are characterized by a relatively wide spectrum of activity, and include nalidixic acid and its 1-ethyl-7-(1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS Registry No. 3703-66-7) ester salt. The latter compound has the following structure: ##STR1## The quinolone nalidixic acid has been investigated in humans as a urinary tract antibacterial agent, but its mechanism of action has not been established. Moreover, nalidixic acid has been linked with the phenomenon of "pseudomembranous colitis". Pseudomembranous colitis, which is characterized by inflammation of the mucosa of the colon and sometimes accompanied by massive watery diarrhea, is a significant cause of morbidity in hospitalized patients. U.S. Pat. No. 4,751,234, issued to Fink et al., describes the compound of the structure ##STR2## as useful in the treatment of pseudomembranous colitis. European Patent Application No. 29,528, published Mar. 31, 1981, describes a number of 5-amino-1,2,4-thiadiazoles. However, the compounds of the present invention are not disclosed or suggested in that document.Q: How to open up Admin panel in crm 4.0? I am trying to open up the CRM 4.0 Admin Panel. I logged in with the same user as earlier. But after logging in I can see a black page and can't open the Admin Panel. How do I open it? A: In 4.0, the admin pages are in a different application called 'CrmCoreWeb'. If you have a CRM installation you can get this by visiting (replacing CRM_INSTANCE with your CR

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